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Subcutaneous T-cell lymphoma : ウィキペディア英語版
Subcutaneous T-cell lymphoma
Subcutaneous T-cell lymphoma (also known as a "Panniculitis-like T-cell lymphoma") is a cutaneous condition that most commonly presents in young adults, and is characterized by subcutaneous nodules.
==Classification==
Subcutaneous panniculitis-like T-cell lymphoma, is a subtype of Peripheral T-cell lymphoma. Peripheral T-cell lymphoma (PTCL) is defined as a diverse group of aggressive lymphomas that develop from mature-stage white blood cells called T-cells and natural killer cells (NK cells) (see figure for an overview of PTCL subtypes). PTCL is a type of non-Hodgkin’s lymphoma (NHL).〔Swerdlow SH, ''WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues'', 2008〕 NHL affects two particular types of white blood cells: B-cells and T-cells. PTCL specifically affects T-cells, and results when T-cells develop and grow abnormally.
File:PTCL-subtypes.jpg
Subcutaneous Panniculitis-like T-cell Lymphoma is a rare type of lymphoma that infiltrates the subcutaneous fat but does not involve the skin. There are two subtypes – alpha-beta and gamma-delta. Patients with the gamma-delta subtype have a more aggressive clinical course.
It is described as CD3+/CD4-/CD8+, with CD30 and CD56 usually negative.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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